By Dr. Dimitar Marinov

medical reviewed by Best HGH Doctors and Clinics dedicated team.

Evidence basedThis article is reviewed by medical professionals for the relevancy and accuracy of the content. Every article is evidence-based and contains references to peer-reviewed studies and academic research.

Experiencing problems with bad concentration, low energy levels, and hypersensitivity? These are common symptoms of growth hormone deficiency (GHD) which can significantly impair your general well-being and quality of life.

Impaired quality of life and psychological complaints

GHD patients have significantly lower indicators for quality of life such as decreased psychological well‐being, low energy levels, disturbed sex life, and increased social isolation when compared to healthy people.

GHD leads to muscle loss and abdominal fat gain that can impact your body image. It can cause unhappiness with the way you look and low self-esteem which will have a negative effect on your quality of life.

Cognitive performance is also affected in patients with GHD. When compared to healthy controls, GHD patients have various degrees of cognitive impairment, including poor concentration and memory problems.

Other health problems that can reduce your quality of life include debilitating chronic conditions, mental health problems, and malignancies.

How HGH Affects the Quality of Life

HGH plays a role in the normal function of multiple systems and processes in your body. These include sensitivity to pain, energy levels, body composition, and even cognition.

HGH is vital for optimal memory, learning abilities, and emotional well-being

Low HGH can also impact your normal perception of pain and lead to hypersensitivity. A systematic review of more than 50 studies has linked GHD and low IGF-1 (insulin-like growth factor 1) levels to hypersensitivity towards pain and temperature.

How to Improve Your Quality of Life with GHD

Quality of life can be accessed by various methods and questionnaires. Most of those methods report significant improvement in GHD patients after GH replacement therapy. Some of the most notable changes include improved scores of anxiety, vitality, cognition, mood, and behavior.

Long-term HGH is required to achieve an optimal effect on your quality of life. About 6 months of treatment with HGH is enough to achieve significant improvements in psychological well-being, energy levels, and mood.

The cognitive problems related to GHD can also be successfully reversed during HGH therapy. It leads to improved attention and memory in all patients when compared to their pretreatment condition.

Treatment with recombinant GH is effective in reducing hypersensitivity, as well. A study with 120 participants has revealed that 12 months of HGH therapy can reduce pain and improve quality of life in patients with fibromyalgia. Also, treatment with recombinant HGH can reduce pain and hypersensitivity in patients with chronic low back pain.

Another symptom that severely impairs quality of life is chronic fatigue and lack of motivation. In fact, low energy levels and reduced productivity are some of the first GHD symptoms which patients seek to address.

Discover more about lack of motivation and energy


Lack of motivation and energy


GHD can reduce your motivation and capability to perform physical tasks. Patients with GH deficiency often experience a lack of energy, chronic fatigue and decreased productivity

Find out more